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However, scarce information is available about the molecular characteristics of HIV in IBM.

The main objectives of this study are to investigate the dynamics of MSM seeking homosexual partners through the Internet, the prevalence of HIV and its trends over time among IBM and NIBM, factors correlating with HIV infection among IBM and NIBM, and the difference in HIV subtypes and HIV transmitted drug resistance (TDR) rates between IBM and NIBM in Shenyang, China.

These studies examined HIV testing and sexual behaviors and mainly found that IBM are usually younger, have higher educational level, and are more likely to test for HIV compared with non-Internet-based MSM [NIBM] [6–11].

A few studies compared the prevalence of HIV and sexually transmitted infections (STIs) between IBM and NIBM, but with inconclusive evidence on whether online partner-seeking increased the prevalence of HIV and or STIs [5, 9].

The VCT clinic provides the largest free HIV testing and counseling service in Shenyang.

Out of the newly reported HIV/AIDS cases in China in 2015, 28.3% were from the MSM population [2], while in 2011, MSM only accounted for 13.7% of newly reported cases [3].The subtypes of HIV are quite diverse in the MSM population, with the subtypes correlating with geographic location, transmission routes, and even sexual characteristics [14–16].HIV bioinformatics analysis has been used to elucidate the transmission origin, transmission routes, and evolutionary dynamics of HIV in MSM and other populations [17].Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China Received 7 September 2016; Revised 16 November 2016; Accepted 1 December 2016Academic Editor: Lei Zhang Copyright © 2016 Shi Pan et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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More efforts should be targeted towards developing interventions aimed at IBM, particularly migrant MSM and who engage in UAI with casual homosexual partners.

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